PeptideEmergingGrowth Hormone Secretagogue

GHRP-2

Typical dose

100–300 mcg

1–3×/day · SubQ

Half-life

~1–2 hours

What is GHRP-2?

Potent GH-releasing hexapeptide. Strongly stimulates GH and mildly raises cortisol and prolactin.

How GHRP-2 works

Binds the ghrelin receptor to trigger a strong GH pulse from the pituitary, with moderate ACTH and cortisol co-release — more potent but less selective than Ipamorelin.

Benefits & uses

Strong GH release
Appetite stimulation
Muscle growth
Recovery

Common uses: GH release, muscle recovery, body composition, appetite stimulation.

GHRP-2 dosage

Typical dose: Typical: 100–300 mcg per dose SubQ, 1–3×/day. 8–12 week blocks.
Protocol notes: 100-300mcg, 2-3x daily. Must fast 30+ min before and after injection.

GHRP-2 half-life

~1–2 hours

GHRP-2 side effects

Elevated cortisol and prolactin. Strong hunger. Water retention.

Elevated cortisol (blunts benefits of GH at high doses)
Prolactin increase — monitor with dopamine agonist
Strong appetite stimulation
Water retention and puffiness

Warnings & monitoring

Research use only
Raises cortisol and prolactin
Increases appetite significantly
Fast 30+ min before injecting

Preparation & storage

Preparation: Mix a 5 mg vial with 2 mL bac water → 2,500 mcg/mL. A 200 mcg dose = 0.08 mL = 8 units.
Reconstitution: Reconstitute a 5 mg vial with 2 mL BAC water → 2.5 mg/mL. A 200 mcg dose = 0.08 mL = 8 units on a U-100 syringe.
Storage: Lyophilized: refrigerate (2–8 °C). Reconstituted: refrigerate, use within 30 days.

GHRP-2 interactions

with GHRP-6
Caution · mild
Both bind the same ghrelin receptor; combining only stacks cortisol/prolactin elevation and appetite stimulation without proportional GH gain.
Timing: Do not stack — choose one GHRP
with GHRP-6
Caution · low
GHRP-2 and GHRP-6 both stimulate GH release through ghrelin receptors. Stacking two GHRPs offers minimal additional benefit over a single GHRP + CJC-1295 combo. GHRP-6 causes significant hunger.
Timing: Avoid stacking two GHRPs — choose one and add a GHRH analog
with CJC-1295
Compatible
GHRP-2 produces a strong GH pulse that is amplified by CJC-1295's GHRH effect, though GHRP-2 causes more cortisol and prolactin release than Ipamorelin.
Timing: Inject together on an empty stomach; allow 2 hours post-meal

Commonly stacked with

CJC-1295 (no DAC)Sermorelin BPC-157

Track GHRP-2 in Protokol.

Log doses, model half-lives, check interactions, and line it all up against your bloodwork. Free on iPhone and Android.