PeptideEmergingGrowth Hormone Secretagogue

GHRP-6

Typical dose

100–300 mcg

1–3×/day · SubQ · strong hunger

Half-life

~15–60 minutes

What is GHRP-6?

Potent GH-releasing peptide. Causes significant hunger increase. Use before meals or in a bulking phase.

How GHRP-6 works

Binds the ghrelin receptor and stimulates GH secretion from the anterior pituitary; produces the strongest appetite stimulation of all GHRPs due to high ghrelin mimicry.

Benefits & uses

Strong GH release
Appetite stimulation
Muscle growth

Common uses: GH release, muscle mass, appetite stimulation, healing.

GHRP-6 dosage

Typical dose: Typical: 100–300 mcg per dose SubQ, 1–3×/day (strong hunger). 8–12 week blocks.
Protocol notes: 100-300mcg per injection. Expect intense hunger 20-30 min post-injection.

GHRP-6 half-life

~15–60 minutes

GHRP-6 side effects

Strong hunger (ghrelin effect). Water retention, cortisol increase.

Strong hunger/ghrelin effect within 20 min of injection
Elevated cortisol
Prolactin increase
Water retention
Not suitable for fat-loss phases

Warnings & monitoring

Research use only
Intense appetite stimulation
Raises cortisol and prolactin
Fast before injecting

Preparation & storage

Preparation: Mix a 5 mg vial with 2 mL bac water → 2,500 mcg/mL. A 200 mcg dose = 0.08 mL = 8 units.
Reconstitution: Reconstitute a 5 mg vial with 2 mL BAC water → 2.5 mg/mL. A 200 mcg dose = 0.08 mL = 8 units on a U-100 syringe.
Storage: Lyophilized: refrigerate (2–8 °C). Reconstituted: refrigerate, use within 30 days.

GHRP-6 interactions

with GHRP-2
Caution · mild
Both bind the same ghrelin receptor; combining only stacks cortisol/prolactin elevation and appetite stimulation without proportional GH gain.
Timing: Do not stack — choose one GHRP
with GHRP-2
Caution · low
GHRP-2 and GHRP-6 both stimulate GH release through ghrelin receptors. Stacking two GHRPs offers minimal additional benefit over a single GHRP + CJC-1295 combo. GHRP-6 causes significant hunger.
Timing: Avoid stacking two GHRPs — choose one and add a GHRH analog
with Ipamorelin
Caution · mild
Both are ghrelin receptor agonists (GHRPs) — stacking them provides minimal additive GH release while compounding hunger, cortisol, and prolactin side effects.
Timing: Do not combine in the same injection window; choose one GHRP per session
with CJC-1295
Compatible
A potent GH-amplifying combination, but GHRP-6's strong ghrelin activity causes significant appetite stimulation — best used during a caloric surplus.
Timing: Inject together fasted; be aware of strong hunger response within 20 min

Commonly stacked with

CJC-1295 (no DAC)Sermorelin

Track GHRP-6 in Protokol.

Log doses, model half-lives, check interactions, and line it all up against your bloodwork. Free on iPhone and Android.