CJC-1295 (no DAC)
Typical dose
100 mcg
1–3×/day · SubQ · pulsed w/ a GHRP
Half-life
30 minutes
What is CJC-1295 (no DAC)?
Short-acting GHRH analog without the Drug Affinity Complex. Produces cleaner, more natural GH pulses matching endogenous patterns.
How CJC-1295 (no DAC) works
Same GHRH receptor binding as DAC version but rapidly cleared from circulation.
Benefits & uses
- GH pulse stimulation
- Muscle retention
- Fat loss
- Sleep improvement
- Recovery
Common uses: GH stimulation, body composition, recovery, sleep quality, anti-aging.
CJC-1295 (no DAC) dosage
- Typical dose
- Typical: 100 mcg per dose SubQ, 1–3×/day, pulsed (often paired with a GHRP). 8–12 week blocks.
- Protocol notes
- 100-300mcg per injection. Always combine with a GHRP like Ipamorelin for maximum GH pulse.
CJC-1295 (no DAC) half-life
30 minutes
CJC-1295 (no DAC) side effects
Minor injection site reactions, tingling, flushing.
- Minor injection site reactions
- Tingling
- Flushing
Warnings & monitoring
- Research use only
- Do not use within 1-2h of eating (blunts GH pulse)
- Avoid in active cancer
Preparation & storage
- Preparation
- Mix a 5 mg vial with 2 mL bac water → 2,500 mcg/mL. A 100 mcg dose = 0.04 mL = 4 units.
- Reconstitution
- Reconstitute a 5 mg vial with 2 mL BAC water → 2.5 mg/mL. A 100 mcg dose = 0.04 mL = 4 units on a U-100 syringe.
- Storage
- Lyophilized: refrigerate (2–8 °C). Reconstituted: refrigerate, use within 21–30 days.
CJC-1295 (no DAC) interactions
with Insulin
Caution · moderateGH peptides elevate fasting glucose and may interfere with insulin sensitivity; close glucose monitoring required when stacking.
Timing: Separate dosing windows by 2+ hours
with Sermorelin
Caution · mildBoth are GHRH analogs targeting the same receptor — combining provides no additive GH release and wastes peptide. Pick the longer-acting CJC-1295 for steady elevation.
Timing: Choose one GHRH analog; do not stack
with Tesamorelin
Caution · mildTesamorelin and CJC-1295 are both GHRH analogs. Stacking offers no synergy; redundant receptor competition just doubles cost.
Timing: Choose one GHRH analog per protocol
with AOD-9604
CompatibleAOD-9604 targets fat metabolism without binding the GH receptor; pairs cleanly with GHRH analogs for body-comp protocols.
Timing: AOD-9604 morning + CJC nightly
with GHRP-2
CompatibleGHRP-2 produces a strong GH pulse that is amplified by CJC-1295's GHRH effect, though GHRP-2 causes more cortisol and prolactin release than Ipamorelin.
Timing: Inject together on an empty stomach; allow 2 hours post-meal
with GHRP-6
CompatibleA potent GH-amplifying combination, but GHRP-6's strong ghrelin activity causes significant appetite stimulation — best used during a caloric surplus.
Timing: Inject together fasted; be aware of strong hunger response within 20 min
with Hexarelin
Compatible · lowHexarelin (GHRP) + CJC-1295 (GHRH analog) is a potent GH-releasing combination. Hexarelin is more potent than Ipamorelin but less selective. Cortisol and prolactin may also be elevated.
Timing: Administer together subcutaneously; fasted state preferred for maximum GH pulse
with Hexarelin
CompatibleHexarelin is a potent GHRP that synergizes with CJC-1295, but desensitizes more rapidly than Ipamorelin — cycle use and avoid daily dosing.
Timing: Inject together fasted; use 2–3x per week to reduce desensitization
with Hexarelin
CompatibleHexarelin is a potent GHRP; CJC-1295 sustains the resulting GH pulse. Watch cortisol/prolactin and rotate off hexarelin to preserve sensitivity.
Timing: Co-inject; cycle 4 weeks on, 2 off due to receptor desensitization
with Ipamorelin
CompatibleThe gold-standard GH peptide stack: CJC-1295 extends the GH pulse while Ipamorelin triggers selective GH release with minimal cortisol or prolactin elevation.
Timing: Inject together 15–30 min before bed or post-workout on an empty stomach
with MK-677
Compatible · lowBoth stimulate GH release through different mechanisms (GHRH analog vs. ghrelin mimetic). Additive GH response expected. MK-677 may increase hunger significantly.
Timing: CJC-1295 pre-bed fasted; MK-677 can be timed similarly for GH pulse synergy
Commonly stacked with
More Growth Hormone Secretagogue
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- GHRP-2Potent GH-releasing hexapeptide. Strongly stimulates GH and mildly raises…
- GHRP-6Potent GH-releasing peptide. Causes significant hunger increase. Use before…
- HexarelinThe most potent synthetic GHRP. Produces large GH pulses but desensitizes…
- IpamorelinPentapeptide GHRP with selective GH release without affecting cortisol or…
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