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PeptideEmergingGrowth Hormone Secretagogue

CJC-1295 (no DAC)

Typical dose

100 mcg

1–3×/day · SubQ · pulsed w/ a GHRP

Half-life

30 minutes

What is CJC-1295 (no DAC)?

Short-acting GHRH analog without the Drug Affinity Complex. Produces cleaner, more natural GH pulses matching endogenous patterns.

How CJC-1295 (no DAC) works

Same GHRH receptor binding as DAC version but rapidly cleared from circulation.

Benefits & uses

  • GH pulse stimulation
  • Muscle retention
  • Fat loss
  • Sleep improvement
  • Recovery

Common uses: GH stimulation, body composition, recovery, sleep quality, anti-aging.

CJC-1295 (no DAC) dosage

Typical dose
Typical: 100 mcg per dose SubQ, 1–3×/day, pulsed (often paired with a GHRP). 8–12 week blocks.
Protocol notes
100-300mcg per injection. Always combine with a GHRP like Ipamorelin for maximum GH pulse.

CJC-1295 (no DAC) half-life

30 minutes

CJC-1295 (no DAC) side effects

Minor injection site reactions, tingling, flushing.

  • Minor injection site reactions
  • Tingling
  • Flushing

Warnings & monitoring

  • Research use only
  • Do not use within 1-2h of eating (blunts GH pulse)
  • Avoid in active cancer

Preparation & storage

Preparation
Mix a 5 mg vial with 2 mL bac water → 2,500 mcg/mL. A 100 mcg dose = 0.04 mL = 4 units.
Reconstitution
Reconstitute a 5 mg vial with 2 mL BAC water → 2.5 mg/mL. A 100 mcg dose = 0.04 mL = 4 units on a U-100 syringe.
Storage
Lyophilized: refrigerate (2–8 °C). Reconstituted: refrigerate, use within 21–30 days.

CJC-1295 (no DAC) interactions

  • with Insulin

    Caution · moderate

    GH peptides elevate fasting glucose and may interfere with insulin sensitivity; close glucose monitoring required when stacking.

    Timing: Separate dosing windows by 2+ hours

  • with Sermorelin

    Caution · mild

    Both are GHRH analogs targeting the same receptor — combining provides no additive GH release and wastes peptide. Pick the longer-acting CJC-1295 for steady elevation.

    Timing: Choose one GHRH analog; do not stack

  • with Tesamorelin

    Caution · mild

    Tesamorelin and CJC-1295 are both GHRH analogs. Stacking offers no synergy; redundant receptor competition just doubles cost.

    Timing: Choose one GHRH analog per protocol

  • with AOD-9604

    Compatible

    AOD-9604 targets fat metabolism without binding the GH receptor; pairs cleanly with GHRH analogs for body-comp protocols.

    Timing: AOD-9604 morning + CJC nightly

  • with GHRP-2

    Compatible

    GHRP-2 produces a strong GH pulse that is amplified by CJC-1295's GHRH effect, though GHRP-2 causes more cortisol and prolactin release than Ipamorelin.

    Timing: Inject together on an empty stomach; allow 2 hours post-meal

  • with GHRP-6

    Compatible

    A potent GH-amplifying combination, but GHRP-6's strong ghrelin activity causes significant appetite stimulation — best used during a caloric surplus.

    Timing: Inject together fasted; be aware of strong hunger response within 20 min

  • with Hexarelin

    Compatible · low

    Hexarelin (GHRP) + CJC-1295 (GHRH analog) is a potent GH-releasing combination. Hexarelin is more potent than Ipamorelin but less selective. Cortisol and prolactin may also be elevated.

    Timing: Administer together subcutaneously; fasted state preferred for maximum GH pulse

  • with Hexarelin

    Compatible

    Hexarelin is a potent GHRP that synergizes with CJC-1295, but desensitizes more rapidly than Ipamorelin — cycle use and avoid daily dosing.

    Timing: Inject together fasted; use 2–3x per week to reduce desensitization

  • with Hexarelin

    Compatible

    Hexarelin is a potent GHRP; CJC-1295 sustains the resulting GH pulse. Watch cortisol/prolactin and rotate off hexarelin to preserve sensitivity.

    Timing: Co-inject; cycle 4 weeks on, 2 off due to receptor desensitization

  • with Ipamorelin

    Compatible

    The gold-standard GH peptide stack: CJC-1295 extends the GH pulse while Ipamorelin triggers selective GH release with minimal cortisol or prolactin elevation.

    Timing: Inject together 15–30 min before bed or post-workout on an empty stomach

  • with MK-677

    Compatible · low

    Both stimulate GH release through different mechanisms (GHRH analog vs. ghrelin mimetic). Additive GH response expected. MK-677 may increase hunger significantly.

    Timing: CJC-1295 pre-bed fasted; MK-677 can be timed similarly for GH pulse synergy

Commonly stacked with

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More Growth Hormone Secretagogue

For research and educational purposes only. This page is not medical advice and is not a recommendation to use any compound. Many compounds listed are not approved for human use, and some are prescription-only or controlled in your jurisdiction. Dosing figures are reference or observational reports. Talk to a qualified healthcare provider before starting, stopping, or changing anything. Protokol is for tracking purposes only.