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Vitamin E (Tocotrienols)

Also known as Vitamin E

Half-life

~2–4 hours

What is Vitamin E (Tocotrienols)?

Superior form of vitamin E with farnesyl tail enabling better membrane penetration and potent neuroprotection.

How Vitamin E (Tocotrienols) works

More potent antioxidant than tocopherols due to faster recycling kinetics. Also inhibit HMG-CoA reductase (like statins) and activate neuroprotective signaling (including suppression of glutamate-induced neuronal death).

Benefits & uses

  • Antioxidant/cell protection
  • Skin health
  • Supports immune function

Common uses: Neuroprotection, cancer prevention, cholesterol reduction, antioxidant protection.

Longevity

Vitamin E (Tocotrienols) dosage

Typical dose
100–200 mg/day of mixed tocotrienols (annatto-derived annatto DeltaGold preferred). Take separately from tocopherols.

Vitamin E (Tocotrienols) half-life

~2–4 hours (plasma)

Vitamin E (Tocotrienols) side effects

Very safe. May interfere with alpha-tocopherol at very high doses.

  • Very low toxicity profile
  • High-dose alpha-tocopherol supplements compete with tocotrienol absorption — avoid combining
  • Well tolerated at normal doses
  • High doses may increase bleeding risk

Warnings & monitoring

  • High doses can increase bleeding risk with anticoagulants

Track Vitamin E (Tocotrienols) in Protokol.

Log doses, model half-lives, check interactions, and line it all up against your bloodwork. Free on iPhone and Android.

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For research and educational purposes only. This page is not medical advice and is not a recommendation to use any compound. Many compounds listed are not approved for human use, and some are prescription-only or controlled in your jurisdiction. Dosing figures are reference or observational reports. Talk to a qualified healthcare provider before starting, stopping, or changing anything. Protokol is for tracking purposes only.