VitaminWell-studiedVitamin

Vitamin B2 (Riboflavin)

Also known as Vitamin B2

Half-life

~66 minutes

What is Vitamin B2 (Riboflavin)?

Water-soluble B vitamin acting as precursor to FAD and FMN coenzymes. Critical for mitochondrial energy production.

How Vitamin B2 (Riboflavin) works

Converted to FAD and FMN coenzymes essential for the electron transport chain, fatty acid beta-oxidation, and regeneration of glutathione (antioxidant defense).

Benefits & uses

Energy metabolism
Antioxidant support
May reduce migraine frequency

Common uses: Energy metabolism, antioxidant recycling, migraine prevention, anemia, skin/eye health.

Vitamin B2 (Riboflavin) dosage

Typical dose: General: 25–100 mg/day. Migraine prevention: 400 mg/day. RDA 1.3 mg — deficiency common in athletes.

Vitamin B2 (Riboflavin) half-life

~66 minutes (plasma); tissue stores 2–6 weeks

Vitamin B2 (Riboflavin) side effects

Very safe. Urine turns bright yellow (harmless). Rare GI upset at very high doses.

Harmless bright yellow urine (riboflavinuria)
Mild GI discomfort at very high doses (rare)
No clinically significant toxicity
Well tolerated
Turns urine bright yellow (harmless)

Track Vitamin B2 (Riboflavin) in Protokol.

Log doses, model half-lives, check interactions, and line it all up against your bloodwork. Free on iPhone and Android.