Supplement
Trans-Resveratrol
Half-life
~1–3 hours
What is Trans-Resveratrol?
Biologically active isomer of resveratrol — superior to cis form for bioavailability and sirtuin activation.
How Trans-Resveratrol works
Trans configuration enables precise binding to SIRT1 active site and interactions with AMPK pathway not available with cis-resveratrol. Typically derived from Japanese knotweed (Polygonum cuspidatum).
Benefits & uses
Common uses: SIRT1 activation, longevity, cardiovascular health, anti-inflammatory.
Trans-Resveratrol dosage
- Typical dose
- 150–500 mg/day with fat-containing meal. More potent per gram than standard resveratrol.
Trans-Resveratrol half-life
~1–3 hours (plasma trans-resveratrol)
Trans-Resveratrol side effects
Better bioavailability than standard resveratrol. Same general safety profile.
- Same as resveratrol but better bioavailability
- Drug interactions with anticoagulants (warfarin)
Commonly stacked with
Track Trans-Resveratrol in Protokol.
Log doses, model half-lives, check interactions, and line it all up against your bloodwork. Free on iPhone and Android.
