SupplementEmergingNootropic
Acetyl-L-Carnitine (ALCAR)
Also known as Acetyl-L-Carnitine (Cognitive), ALCAR, acetyl l carnitine
Half-life
~2-3 hours
What is Acetyl-L-Carnitine (ALCAR)?
Acetylated form of L-carnitine that crosses blood-brain barrier. Supports mitochondrial and cognitive function.
How Acetyl-L-Carnitine (ALCAR) works
Fatty acid transport (like L-carnitine) plus acetyl group donation for acetylcholine synthesis and histone acetylation-mediated gene expression in brain.
Benefits & uses
- Mental energy & focus
- Mitochondrial/cellular energy
- May support mood
- Fatty-acid metabolism
Common uses: Cognitive enhancement, memory, mitochondrial function, neuroprotection, mood.
CognitiveFat Loss
Acetyl-L-Carnitine (ALCAR) dosage
- Typical dose
- 500–2000 mg daily
Acetyl-L-Carnitine (ALCAR) half-life
~2-3 hours (plasma); brain can retain acetyl groups longer
Acetyl-L-Carnitine (ALCAR) side effects
- Fishy odor (less than free L-carnitine)
- Insomnia if taken too late
- Nausea (rare)
- Generally well tolerated
- Overstimulation/insomnia if late
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