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SupplementEmergingAdaptogen

Reishi Mushroom

Also known as Reishi

Half-life

~1-2 hours

What is Reishi Mushroom?

Adaptogenic mushroom with polysaccharides and betaglucans. Traditional immune and stress support.

How Reishi Mushroom works

Activates macrophage and NK cell populations via beta-glucan receptor (Dectin-1). Modulates HPA axis and GABA-A signaling for stress reduction.

Benefits & uses

  • Immune support
  • Stress reduction
  • Sleep support
  • Antioxidant

Common uses: Immune support, stress, sleep, longevity.

RecoveryLongevity

Reishi Mushroom dosage

Typical dose
1–2 g daily (or extract equivalent; evening)

Reishi Mushroom half-life

~1-2 hours (polysaccharides in plasma)

Reishi Mushroom side effects

  • Mild sedation
  • Very safe long-term
  • May take 2-4 weeks for adaptogenic effects
  • Generally well tolerated
  • Rare: dry mouth, GI upset

Warnings & monitoring

  • May add to bleeding risk with anticoagulants

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More Adaptogen

For research and educational purposes only. This page is not medical advice and is not a recommendation to use any compound. Many compounds listed are not approved for human use, and some are prescription-only or controlled in your jurisdiction. Dosing figures are reference or observational reports. Talk to a qualified healthcare provider before starting, stopping, or changing anything. Protokol is for tracking purposes only.