PeptideAnti-inflammatory
KPV
Typical dose
200–500 mcg
1–2×/day · SubQ or oral
Half-life
~1-2 hours
What is KPV?
Anti-inflammatory tripeptide fragment of alpha-MSH used in gut/skin protocols.
How KPV works
Reduces NF-kB driven cytokine transcription and may improve epithelial barrier inflammation.
Benefits & uses
- Anti-inflammatory
- Gut barrier support
- Wound healing
- Immune modulation
KPV dosage
- Typical dose
- Typical: 200–500 mcg/day SubQ or oral. 4–8 weeks.
- Protocol notes
- 500mcg-1mg per injection or orally. Daily for active inflammation, 3x/week for maintenance.
KPV half-life
~1-2 hours
KPV side effects
- Mild GI discomfort
- Injection-site irritation
- Limited controlled data
Warnings & monitoring
- Research use only
Preparation & storage
- Preparation
- Mix a 10 mg vial with 2 mL bac water → 5 mg/mL. A 500 mcg dose = 0.1 mL = 10 units.
- Reconstitution
- Reconstitute a 10 mg vial with 2 mL BAC water → 5 mg/mL. A 500 mcg dose = 0.1 mL = 10 units on a U-100 syringe.
