SupplementWell-studiedAntioxidant

CoQ10 (Ubiquinol)

Also known as CoQ10, CoQ10 Ubiquinol

Half-life

~33 hours

What is CoQ10 (Ubiquinol)?

Active reduced form of CoQ10. Mitochondrial energy carrier and antioxidant. Essential on statins.

How CoQ10 (Ubiquinol) works

Electron carrier in the mitochondrial electron transport chain (Complex I→III). Functions as an antioxidant in its reduced ubiquinol form, protecting mitochondrial membranes. Statins inhibit CoQ10 synthesis (same mevalonate pathway as cholesterol).

Benefits & uses

Cellular/mitochondrial energy
Heart health
Antioxidant
Replenishes statin-related depletion
Better absorbed than ubiquinone

Common uses: Mitochondrial energy, cardiovascular health, statin-induced myopathy, anti-aging.

LongevityRecovery

CoQ10 (Ubiquinol) dosage

Typical dose: 100–200 mg ubiquinol form/day with fat-containing meal. On statins: 200–300 mg/day.

CoQ10 (Ubiquinol) half-life

~33 hours (ubiquinol in plasma)

CoQ10 (Ubiquinol) side effects

May reduce warfarin effect. Generally very safe.

May require dose increase or separation from warfarin
Generally excellent tolerability
Expensive at higher doses
Well tolerated

Commonly stacked with

Omega-3

Track CoQ10 (Ubiquinol) in Protokol.

Log doses, model half-lives, check interactions, and line it all up against your bloodwork. Free on iPhone and Android.