Supplement
Pycnogenol (Pine Bark)
Half-life
~12 hours
What is Pycnogenol (Pine Bark)?
Proprietary pine bark extract from French maritime pine. Extensive clinical research for ED, circulation, and inflammation.
How Pycnogenol (Pine Bark) works
Stimulates NO synthesis in endothelium (erectile and circulatory benefit), inhibits 5-LOX/COX inflammatory enzymes, enhances collagen synthesis, and improves insulin receptor sensitivity.
Benefits & uses
Common uses: Erectile function, circulation, joint inflammation, ADHD, blood pressure, skin health.
Pycnogenol (Pine Bark) dosage
- Typical dose
- 50–200 mg/day with meals. ED/circulation: 80–200 mg/day in divided doses.
Pycnogenol (Pine Bark) half-life
~12 hours (procyanidins in plasma)
Pycnogenol (Pine Bark) side effects
Very safe. Mild GI upset. Headache occasionally. Drug interactions with immunosuppressants.
- Mild GI discomfort
- Occasional headache
- Interacts with immunosuppressants and anticoagulants
Commonly stacked with
Track Pycnogenol (Pine Bark) in Protokol.
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