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Magnesium Malate

Half-life

~42 days

What is Magnesium Malate?

Magnesium bound to malic acid. Best for energy and muscle function — malic acid is a TCA cycle intermediate.

How Magnesium Malate works

Malic acid chelation enhances intestinal magnesium absorption. Malate enters the TCA cycle as an energy substrate alongside the magnesium enzyme cofactor function — particularly useful for ATP synthesis in mitochondria.

Benefits & uses

  • Magnesium + energy support
  • Muscle/fibromyalgia support
  • Gentle on stomach

Common uses: Energy production, fibromyalgia pain, muscle soreness, daytime magnesium repletion.

RecoveryMuscle

Magnesium Malate dosage

Typical dose
200–400 mg elemental magnesium/day in morning (energizing — not ideal at night).

Magnesium Malate half-life

~42 days (tissue magnesium)

Magnesium Malate side effects

Fewer GI effects than citrate. Malic acid can cause mild GI discomfort at high doses.

  • Mild GI discomfort at high doses
  • Better tolerated than magnesium oxide
  • Energizing effect — do not take at bedtime
  • Well tolerated

Track Magnesium Malate in Protokol.

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For research and educational purposes only. This page is not medical advice and is not a recommendation to use any compound. Many compounds listed are not approved for human use, and some are prescription-only or controlled in your jurisdiction. Dosing figures are reference or observational reports. Talk to a qualified healthcare provider before starting, stopping, or changing anything. Protokol is for tracking purposes only.