ProtokolPROTOKOL
AncillaryEmergingSERM

Enclomiphene

SERM

Also known as Androxal

Half-life

~10-12 hours

What is Enclomiphene?

Active isomer of clomiphene with fewer side effects. More selective for LH/FSH stimulation.

How Enclomiphene works

Selective estrogen receptor antagonism at hypothalamus/pituitary raises LH/FSH and endogenous testosterone.

Benefits & uses

Common uses: PCT, natural testosterone restoration, male fertility, TRT alternative.

Enclomiphene dosage

Protokol doesn't recommend doses for prescription or controlled compounds. Any figures below are reference or observational reports — dosing should be set with a qualified clinician.

Reference range
Literature reports ~12.5–25 mg daily; individual, titrated to labsClinical or reference range, not a personal recommendation.

Enclomiphene half-life

~10-12 hours

Enclomiphene side effects

Fewer vision and mood issues than standard clomid. Still possible at higher doses.

  • Visual disturbances (rare)
  • Mood changes
  • Headache
  • Fewer than clomiphene
  • Possible mild mood/vision effects
  • Hot flashes

Warnings & monitoring

  • Prescription medication — requires a doctor + bloodwork. Start alone, adjust on labs; don't over-stack.

Monitoring: Hormone panel (LH/FSH/T/E2) at ~6 weeks, then adjust.

Enclomiphene interactions

  • with Ostarine

    Compatible

    Mild SARM suppression can be supported with low-dose enclomiphene without crashing E2 like Clomid sometimes does.

    Timing: Enclomiphene 12.5mg daily during/after Ostarine to support LH

Commonly stacked with

Track Enclomiphene in Protokol.

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More SERM

For research and educational purposes only. This page is not medical advice and is not a recommendation to use any compound. Many compounds listed are not approved for human use, and some are prescription-only or controlled in your jurisdiction. Dosing figures are reference or observational reports. Talk to a qualified healthcare provider before starting, stopping, or changing anything. Protokol is for tracking purposes only.