ProtokolPROTOKOL
AncillaryWell-studiedProlactin Control

Cabergoline (Dostinex)

Dopamine Agonist

Also known as Dostinex, Cabergoline

Half-life

~63-69 hours

What is Cabergoline (Dostinex)?

Dopamine agonist. Powerfully reduces prolactin. Used with 19-nor compounds (Deca, Tren).

How Cabergoline (Dostinex) works

D2 dopamine receptor agonist suppressing pituitary prolactin secretion.

Benefits & uses

Common uses: Prolactin control (Deca/Tren cycles), libido, ED from prolactin, Parkinson's.

Cabergoline (Dostinex) dosage

Protokol doesn't recommend doses for prescription or controlled compounds. Any figures below are reference or observational reports — dosing should be set with a qualified clinician.

Reference range
Literature reports ~0.25–0.5 mg 1–2×/week; individual, titrated to prolactin labsClinical or reference range, not a personal recommendation.

Cabergoline (Dostinex) half-life

~63-69 hours

Cabergoline (Dostinex) side effects

Dizziness, nausea, headache, cardiac valve issues with long-term use.

  • Nausea/orthostasis
  • Impulse-control effects
  • Valvular risk at high chronic doses
  • Nausea
  • Dizziness/low blood pressure
  • Heart-valve concerns at high chronic doses

Warnings & monitoring

  • Prescription medication — requires a doctor + prolactin bloodwork. Heart-valve risk with high chronic use.

Monitoring: Prolactin bloodwork; cardiac caution at high chronic doses.

Cabergoline (Dostinex) interactions

  • with Trenbolone

    Caution · moderate

    Tren raises prolactin; cabergoline reins it in. Watch for excessive prolactin suppression (low libido, mood) at higher cab doses.

    Timing: Cabergoline 0.25–0.5mg 2×/week alongside Tren cycles

  • with Deca-Durabolin

    Compatible

    19-nor compounds elevate prolactin; cabergoline mitigates the libido/erection issues commonly reported on Deca.

    Timing: Cabergoline 0.25mg 2×/week during nandrolone cycle

  • with Nandrolone

    Compatible · low

    Nandrolone raises prolactin via progesterone receptor activity. Cabergoline (a dopamine agonist) controls prolactin-related side effects including sexual dysfunction and gyno.

    Timing: Start cabergoline 0.25mg 2×/week when running nandrolone above 300mg/week

  • with Trenbolone

    Compatible

    Prophylactic cabergoline controls tren-induced prolactin elevation, mitigating libido and mood side effects.

    Timing: Cabergoline 0.25mg 2×/week during tren cycle

Track Cabergoline (Dostinex) in Protokol.

Log doses, model half-lives, check interactions, and line it all up against your bloodwork. Free on iPhone and Android.

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More Prolactin Control

For research and educational purposes only. This page is not medical advice and is not a recommendation to use any compound. Many compounds listed are not approved for human use, and some are prescription-only or controlled in your jurisdiction. Dosing figures are reference or observational reports. Talk to a qualified healthcare provider before starting, stopping, or changing anything. Protokol is for tracking purposes only.