SupplementEmergingDigestive Health

Bromelain

Half-life

~6–9 hours

What is Bromelain?

Proteolytic enzyme complex from pineapple stem. Used for anti-inflammatory support, recovery, and to improve absorption of co-administered polyphenols like quercetin.

How Bromelain works

Hydrolyzes peptide bonds and modulates prostaglandin/bradykinin pathways, reducing inflammatory mediators and edema.

Benefits & uses

Protein digestion (with food)
Anti-inflammatory (away from food)
May reduce swelling/soreness

Common uses: Anti-inflammatory, proteolytic recovery support, quercetin absorption enhancer, sinus/digestive support.

Recovery

Bromelain dosage

Typical dose: 500 mg 1–3x/day between or with meals; pair with quercetin for synergy.

Bromelain half-life

~6–9 hours (enzymatic activity)

Bromelain side effects

GI upset at high doses
Possible allergy in pineapple-sensitive individuals
Mild anticoagulant effect — caution with blood thinners
Generally well tolerated
Mild GI upset

Commonly stacked with

Quercetin

Track Bromelain in Protokol.

Log doses, model half-lives, check interactions, and line it all up against your bloodwork. Free on iPhone and Android.