ProtokolPROTOKOL
Vitamin

Zinc Picolinate

Half-life

~12 hours

What is Zinc Picolinate?

Highly bioavailable zinc chelated to picolinic acid. Best absorbed zinc form for supplementation.

How Zinc Picolinate works

Picolinate chelation mimics the natural zinc transport mechanism in the gut, enhancing absorption by allowing zinc to pass through intestinal cells more effectively than inorganic zinc salts.

Benefits & uses

Common uses: Testosterone support, immune function, wound healing, skin health.

Zinc Picolinate dosage

Typical dose
15–30 mg/day with food or at bedtime. Slightly lower dose than zinc gluconate due to better bioavailability.

Zinc Picolinate half-life

~12 hours (plasma zinc)

Zinc Picolinate side effects

As with all zinc: GI upset on empty stomach, copper depletion with long-term use.

  • Nausea if taken on empty stomach
  • Copper depletion with chronic use — supplement 2 mg copper

Track Zinc Picolinate in Protokol.

Log doses, model half-lives, check interactions, and line it all up against your bloodwork. Free on iPhone and Android.

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For research and educational purposes only. This page is not medical advice and is not a recommendation to use any compound. Many compounds listed are not approved for human use, and some are prescription-only or controlled in your jurisdiction. Dosing figures are reference or observational reports. Talk to a qualified healthcare provider before starting, stopping, or changing anything. Protokol is for tracking purposes only.