SupplementEmergingJoint Support
UC-II (Undenatured Collagen Type II)
Also known as UC-II Collagen
What is UC-II (Undenatured Collagen Type II)?
Undenatured type II collagen from chicken cartilage. A low-dose joint supplement that works differently from glucosamine/chondroitin.
How UC-II (Undenatured Collagen Type II) works
Works via oral tolerance — small amounts train the immune system to reduce its attack on joint cartilage, lowering inflammation.
Benefits & uses
- Reduces knee osteoarthritis pain
- Improves joint function/mobility
- Outperformed glucosamine+chondroitin in a head-to-head trial
Common uses: Knee osteoarthritis, joint comfort, cartilage support.
Recovery
UC-II (Undenatured Collagen Type II) dosage
- Typical dose
- 40 mg once daily (best on an empty stomach)
UC-II (Undenatured Collagen Type II) side effects
- Generally well tolerated
- No significant adverse effects reported at 40 mg
