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UC-II (Undenatured Collagen Type II)

Also known as UC-II Collagen

What is UC-II (Undenatured Collagen Type II)?

Undenatured type II collagen from chicken cartilage. A low-dose joint supplement that works differently from glucosamine/chondroitin.

How UC-II (Undenatured Collagen Type II) works

Works via oral tolerance — small amounts train the immune system to reduce its attack on joint cartilage, lowering inflammation.

Benefits & uses

  • Reduces knee osteoarthritis pain
  • Improves joint function/mobility
  • Outperformed glucosamine+chondroitin in a head-to-head trial

Common uses: Knee osteoarthritis, joint comfort, cartilage support.

Recovery

UC-II (Undenatured Collagen Type II) dosage

Typical dose
40 mg once daily (best on an empty stomach)

UC-II (Undenatured Collagen Type II) side effects

  • Generally well tolerated
  • No significant adverse effects reported at 40 mg

Commonly stacked with

Track UC-II (Undenatured Collagen Type II) in Protokol.

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For research and educational purposes only. This page is not medical advice and is not a recommendation to use any compound. Many compounds listed are not approved for human use, and some are prescription-only or controlled in your jurisdiction. Dosing figures are reference or observational reports. Talk to a qualified healthcare provider before starting, stopping, or changing anything. Protokol is for tracking purposes only.