ProtokolPROTOKOL
Medication

Trazodone

Half-life

~6-9 hours

What is Trazodone?

Serotonin antagonist/reuptake inhibitor commonly used at low dose for sleep.

How Trazodone works

5-HT2A antagonism and antihistaminic/alpha1-blocking activity drive sedative effects at low doses.

Trazodone half-life

~6-9 hours

Trazodone side effects

  • Morning grogginess
  • Orthostatic hypotension
  • Rare priapism

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For research and educational purposes only. This page is not medical advice and is not a recommendation to use any compound. Many compounds listed are not approved for human use, and some are prescription-only or controlled in your jurisdiction. Dosing figures are reference or observational reports. Talk to a qualified healthcare provider before starting, stopping, or changing anything. Protokol is for tracking purposes only.