Nootropic
Tianeptine
Half-life
~2
What is Tianeptine?
Atypical antidepressant with mu-opioid receptor activity and glutamatergic modulation.
How Tianeptine works
At therapeutic doses modulates glutamate stress signaling; active metabolite has MOR agonism contributing to abuse risk.
Tianeptine half-life
~2.5-3 hours
Tianeptine side effects
- Dependence and withdrawal risk
- Respiratory depression at misuse doses
- Constipation
