Supplement
Theobromine
Half-life
7–12 hours
What is Theobromine?
Methylxanthine found in cacao. Milder, longer-lasting stimulant than caffeine without jitteriness.
How Theobromine works
Weak phosphodiesterase inhibitor and adenosine antagonist. Causes sustained bronchodilation and cardiovascular vasodilation via cardiovascular smooth muscle relaxation — less CNS stimulation than caffeine.
Benefits & uses
Common uses: Smooth energy, focus, cardiovascular vasodilation, mood enhancement, appetite modulation.
Theobromine dosage
- Typical dose
- 300–600 mg/day. Often stacked with caffeine for smoother energy curve.
Theobromine half-life
7–12 hours (longer than caffeine)
Theobromine side effects
Very well tolerated. High doses may cause headache or GI upset. Mild diuretic effect.
- Mild headache at high doses (uncommon)
- Mild diuretic effect
- No significant dependency risk at supplemental doses
Track Theobromine in Protokol.
Log doses, model half-lives, check interactions, and line it all up against your bloodwork. Free on iPhone and Android.
