Testolone (RAD-140)

What is Testolone (RAD-140)?

High-potency SARM with pronounced strength and lean-mass effects.

How Testolone (RAD-140) works

Potent androgen receptor agonist with high tissue selectivity toward muscle and bone.

Benefits & uses

• High anabolic potency (lean mass/strength)
• Strong muscle gains
• Reputation as one of the strongest SARMs

Common uses: Lean mass, strength, recomp, aggressive bulking.

Testolone (RAD-140) dosage

Testolone (RAD-140) half-life

Testolone (RAD-140) side effects

Strong suppression, mood effects, lipid and liver marker changes.

Warnings & monitoring

• 🔴 Unlike the 'SARMs are safe' myth, RAD-140 has documented liver injury — requires liver + lipid + hormone bloodwork + medical monitoring
• Strongly suppressive — PCT needed
• FDA-warned / WADA-banned / gray-market
• Not approved for human use

Preparation & storage

Testolone (RAD-140) interactions

• with LGD-4033

  Avoid · moderate

  Stacking strong SARMs at full dose maximizes HPTA suppression and lipid disruption. Use only one anabolic SARM at a time at meaningful doses.

  Timing: Do not run 3+ SARMs concurrently

• with LGD-4033

  Caution · moderate

  Both are highly suppressive SARMs — stacking significantly increases HPTA suppression and may require aggressive PCT. Combined androgenic load increases hair loss risk in predisposed individuals.

  Timing: Use lower doses of each if stacking; run no longer than 8 weeks

• with LGD-4033

  Caution · moderate

  Both are potent SARMs with significant testosterone suppression. Stacking amplifies suppression without proportional benefits. PCT required after either, especially together.

  Timing: Avoid stacking unless experienced — run one SARM per cycle for better assessment

• with LGD-4033

  Caution · high

  Both LGD-4033 and RAD-140 are among the most suppressive SARMs. Stacking them without exogenous testosterone can lead to severe hypogonadism. Full PCT required post-cycle.

  Timing: Avoid stacking these two aggressive SARMs — suppression is severe

• with Testosterone

  Caution · moderate

  RAD-140 suppresses endogenous testosterone like exogenous androgens. Running both simultaneously is redundant and increases suppression without clear synergy. Choose one approach.

  Timing: Typically not stacked — RAD-140 is an alternative to exogenous testosterone

• with YK-11

  Caution · high

  YK-11 is a myostatin inhibitor with SARM properties and significant anabolic effect. Stacking with RAD-140 creates very high suppression. Exogenous testosterone as a base is strongly recommended.

  Timing: Advanced-only stack; expect full suppression requiring testosterone base or PCT

• with YK-11

  Caution · moderate

  YK-11 is a myostatin inhibitor with steroidal structure — highly potent and suppressive. Combined with RAD-140, androgenic load is significant. This stack is closer to a mild steroid cycle in terms of HPTA impact.

  Timing: Use low doses of each; 8-week maximum; PCT required

• with Cardarine

  Compatible

  Cardarine (GW-501516) is not a SARM but a PPAR-delta agonist — it has no androgenic activity and complements RAD-140's anabolic effects with enhanced endurance and fat oxidation.

  Timing: Take both daily; Cardarine pre-workout, RAD-140 in the morning

• with MK-677

  Compatible · low

  Common performance stack. RAD-140 provides androgenic muscle/strength effects while MK-677 boosts GH/IGF-1 for recovery and body composition. MK-677 can increase water retention.

  Timing: MK-677 can be run year-round; RAD-140 cycled in blocks

• with MK-677

  Compatible

  MK-677 (Ibutamoren) is a GH secretagogue, not a SARM — no androgenic suppression. Combined with RAD-140 it provides complementary anabolic stimulus (GH-axis + androgen receptor) without additive suppression.

  Timing: MK-677 before bed; RAD-140 in the morning

Commonly stacked with