Telmisartan
Also known as Micardis, ARB, blood pressure, PPAR
Half-life
~24 hours
What is Telmisartan?
ARB (angiotensin receptor blocker) with unique PPAR-gamma partial agonism. Used for hypertension and cardiovascular protection. Popular in longevity/performance circles for blood pressure management during AAS cycles and PPAR-gamma metabolic benefits. Only ARB with significant PPAR-gamma activity.
How Telmisartan works
Selectively blocks the angiotensin II type 1 receptor (AT1) for blood pressure reduction; uniquely also a partial PPAR-gamma agonist providing metabolic benefits (improved insulin sensitivity).
Benefits & uses
- Blood pressure control
- Cardiovascular protection
- PPAR-gamma metabolic benefits
- Insulin sensitization
- Renal protection
Common uses: Blood pressure control, cardiovascular protection, insulin sensitization, renal protection.
Telmisartan dosage
Protokol doesn't recommend doses for prescription or controlled compounds. Any figures below are reference or observational reports — dosing should be set with a qualified clinician.
- Typical dose
- 20-80mg daily oral
- Protocol notes
- 20-80mg once daily. Take at same time each day. Commonly 40mg for longevity/performance use, 80mg for hypertension management.
Telmisartan half-life
~24 hours
Telmisartan side effects
- Dizziness
- Hyperkalemia
- Renal impairment at high doses
Warnings & monitoring
- Prescription medication
- Do not use in pregnancy — category D
- Monitor potassium — hyperkalemia risk
- Do not combine with ACE inhibitors
- Monitor blood pressure and renal function
Telmisartan interactions
with Cardarine
CompatibleTelmisartan's PPAR-gamma activation complements Cardarine's PPAR-delta agonism and helps control AAS-driven BP elevation.
Timing: Telmisartan 40mg daily during Cardarine + harsh AAS cycles
with Testosterone
CompatibleTelmisartan (an ARB) is used alongside TRT for blood pressure management, cardioprotection, and potential PPAR-δ agonist benefits for endurance and metabolism.
Timing: Telmisartan taken daily as cardioprotective agent on TRT
Commonly stacked with
Track Telmisartan in Protokol.
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