ProtokolPROTOKOL
Medication

Sulfasalazine

Half-life

Parent ~7-15 hours

What is Sulfasalazine?

5-ASA prodrug used for inflammatory bowel disease and rheumatoid disease control.

How Sulfasalazine works

Colonic bacterial cleavage releases anti-inflammatory mesalamine and immunomodulatory sulfapyridine effects.

Sulfasalazine half-life

Parent ~7-15 hours; metabolite sulfapyridine longer

Sulfasalazine side effects

  • GI upset
  • Rash/hypersensitivity
  • Folate depletion and lab monitoring needs

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For research and educational purposes only. This page is not medical advice and is not a recommendation to use any compound. Many compounds listed are not approved for human use, and some are prescription-only or controlled in your jurisdiction. Dosing figures are reference or observational reports. Talk to a qualified healthcare provider before starting, stopping, or changing anything. Protokol is for tracking purposes only.