Supplement
R-Alpha Lipoic Acid (R-ALA)
Half-life
~30 minutes
What is R-Alpha Lipoic Acid (R-ALA)?
Biologically active R isomer of alpha lipoic acid — more potent than racemic ALA at lower doses.
How R-Alpha Lipoic Acid (R-ALA) works
The naturally occurring R isomer that serves as the actual mitochondrial cofactor, providing superior bioavailability and efficacy vs racemic ALA per milligram. Na-R-ALA (sodium form) most stable.
Benefits & uses
Common uses: Insulin sensitivity, antioxidant, neuropathy, heavy metal chelation.
R-Alpha Lipoic Acid (R-ALA) dosage
- Typical dose
- 100–200 mg R-ALA = 200–400 mg racemic ALA. Take before meals.
R-Alpha Lipoic Acid (R-ALA) half-life
~30 minutes (plasma R-ALA)
R-Alpha Lipoic Acid (R-ALA) side effects
More potent insulin sensitizer — lower hypoglycemia threshold. GI effects.
- Greater blood glucose lowering at lower doses — increased hypoglycemia risk in diabetics
- GI upset
Track R-Alpha Lipoic Acid (R-ALA) in Protokol.
Log doses, model half-lives, check interactions, and line it all up against your bloodwork. Free on iPhone and Android.
