ProtokolPROTOKOL
Medication

Metformin XR

Half-life

~6-8 hours

What is Metformin XR?

Extended-release metformin formulation for smoother GI tolerance and once-daily control.

How Metformin XR works

Same AMPK and hepatic glucose-output suppression with prolonged intestinal release kinetics.

Metformin XR half-life

~6-8 hours (extended absorption window)

Metformin XR side effects

  • GI upset (usually less than IR)
  • B12 depletion long-term
  • Contraindicated in significant renal dysfunction

Track Metformin XR in Protokol.

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For research and educational purposes only. This page is not medical advice and is not a recommendation to use any compound. Many compounds listed are not approved for human use, and some are prescription-only or controlled in your jurisdiction. Dosing figures are reference or observational reports. Talk to a qualified healthcare provider before starting, stopping, or changing anything. Protokol is for tracking purposes only.