Medication
Metformin XR
Half-life
~6-8 hours
What is Metformin XR?
Extended-release metformin formulation for smoother GI tolerance and once-daily control.
How Metformin XR works
Same AMPK and hepatic glucose-output suppression with prolonged intestinal release kinetics.
Metformin XR half-life
~6-8 hours (extended absorption window)
Metformin XR side effects
- GI upset (usually less than IR)
- B12 depletion long-term
- Contraindicated in significant renal dysfunction
