ProtokolPROTOKOL
Supplement

Lutein + Zeaxanthin

Half-life

~5–7 days

What is Lutein + Zeaxanthin?

Carotenoids that concentrate in the macula of the eye. Essential for blue light protection and macular health.

How Lutein + Zeaxanthin works

Filter high-energy blue light before it reaches photoreceptors, quench singlet oxygen and free radicals in the macula, and reduce neuroinflammation in the brain (lutein is the predominant carotenoid in brain tissue).

Benefits & uses

Common uses: Macular degeneration prevention, blue light filtering, visual acuity, cognitive function.

Lutein + Zeaxanthin dosage

Typical dose
10–20 mg lutein + 2–4 mg zeaxanthin daily with fat. AREDS2 formula: 10 mg lutein + 2 mg zeaxanthin.

Lutein + Zeaxanthin half-life

~5–7 days (carotenoid half-life in plasma)

Lutein + Zeaxanthin side effects

Very safe. High doses may cause yellowish skin tint (carotenodermia — harmless).

  • Harmless yellow-orange skin tint at high doses (carotenodermia)
  • Very safe overall

Track Lutein + Zeaxanthin in Protokol.

Log doses, model half-lives, check interactions, and line it all up against your bloodwork. Free on iPhone and Android.

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For research and educational purposes only. This page is not medical advice and is not a recommendation to use any compound. Many compounds listed are not approved for human use, and some are prescription-only or controlled in your jurisdiction. Dosing figures are reference or observational reports. Talk to a qualified healthcare provider before starting, stopping, or changing anything. Protokol is for tracking purposes only.