Medication
Losartan
Half-life
~2 hours parent
What is Losartan?
Angiotensin receptor blocker (ARB) for BP and renal/cardiac protection.
How Losartan works
AT1 receptor antagonism reduces vasoconstriction and aldosterone signaling without ACE-related bradykinin cough.
Losartan half-life
~2 hours parent; active metabolite ~6-9 hours
Losartan side effects
- Hyperkalemia
- Dizziness
- Renal function changes early in therapy
