Peptide
Larazotide (AT-1001)
Typical dose
500 mcg
before meals, up to 3×/day · oral
Half-life
~1 hour
What is Larazotide (AT-1001)?
Oral tight-junction modulator studied for celiac-related gut permeability.
How Larazotide (AT-1001) works
Antagonizes zonulin-mediated tight-junction opening to reduce paracellular antigen leak in intestine.
Larazotide (AT-1001) dosage
- Typical dose
- Typical: 0.5 mg (500 mcg) before meals, up to 3×/day, oral.
Larazotide (AT-1001) half-life
~1 hour (local GI action)
Larazotide (AT-1001) side effects
- Abdominal discomfort
- Nausea
- Headache
Preparation & storage
- Preparation
- Oral — no mixing needed. Taken before meals.
- Reconstitution
- Oral — no reconstitution.
Track Larazotide (AT-1001) in Protokol.
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