Supplement
L-Tryptophan
Half-life
~1-2 hours
What is L-Tryptophan?
Essential amino acid precursor to serotonin and melatonin. Low in most foods.
How L-Tryptophan works
Converted to 5-hydroxytryptophan (5-HTP) then serotonin (CNS) and kynurenine (peripheral). Also substrate for melatonin synthesis.
Benefits & uses
Common uses: Serotonin support, sleep quality, mood, anxiety reduction.
L-Tryptophan half-life
~1-2 hours (plasma)
L-Tryptophan side effects
- Nausea on empty stomach
- Insomnia if timing is off or dose too close to other amino acids
- Carcinoid syndrome interaction (tryptophan metabolism)
Track L-Tryptophan in Protokol.
Log doses, model half-lives, check interactions, and line it all up against your bloodwork. Free on iPhone and Android.
