Supplement
L-Leucine
Half-life
~1-2 hours
What is L-Leucine?
Essential branched-chain amino acid with unique mTORC1-activating properties. Directly stimulates muscle protein synthesis.
How L-Leucine works
Activates GATOR2 (bypasses leucine sensors) to directly activate mTORC1 — triggers protein synthesis even with suboptimal amino acid availability.
Benefits & uses
Common uses: Muscle protein synthesis, appetite control, strength gains, anti-catabolic.
L-Leucine half-life
~1-2 hours
L-Leucine side effects
- High intakes may suppress other amino acids' oxidation
- Can elevate ammonia (branched-chain amino acid metabolism)
- Nausea on empty stomach
Track L-Leucine in Protokol.
Log doses, model half-lives, check interactions, and line it all up against your bloodwork. Free on iPhone and Android.
