ProtokolPROTOKOL
Supplement

Kava Kava

Half-life

~2-3 hours

What is Kava Kava?

Root extract from South Pacific with kavalactones. Traditional anxiolytic.

How Kava Kava works

Kavalactones modulate GABA-A and GABA-C receptors. Blocks dopaminergic loss in anxiety circuits. Muscle-relaxing properties via voltage-gated channel effects.

Kava Kava half-life

~2-3 hours (kavalactones in plasma)

Kava Kava side effects

  • Hepatotoxicity potential — liver monitoring advisable with chronic use
  • May potentiate sedative effects with other CNS depressants
  • Dermopathy (skin scaling) with chronic high-dose use

Track Kava Kava in Protokol.

Log doses, model half-lives, check interactions, and line it all up against your bloodwork. Free on iPhone and Android.

Download on the App StoreGet it on Google Play

For research and educational purposes only. This page is not medical advice and is not a recommendation to use any compound. Many compounds listed are not approved for human use, and some are prescription-only or controlled in your jurisdiction. Dosing figures are reference or observational reports. Talk to a qualified healthcare provider before starting, stopping, or changing anything. Protokol is for tracking purposes only.