PeptideEmergingAnabolic

IGF-1 LR3

Typical dose

20–50 mcg

once daily (post-workout) · SubQ · 4 on/4 off

Half-life

~20-30 hours

What is IGF-1 LR3?

Long-acting form of IGF-1 with reduced binding to IGF binding proteins, extending activity and anabolic signaling.

Activates IGF-1 receptors and downstream PI3K/AKT signaling to increase protein synthesis and cellular growth.

Common uses: Muscle hypertrophy, recovery, hyperplasia stimulation, nutrient partitioning.

Typical dose: Typical: 20–50 mcg/day SubQ (local or systemic). Short cycles (4 on / 4 off).

~20-30 hours

Hypoglycemia, edema, headache, theoretical cancer promotion risk.

Preparation: Mix a 1 mg vial with 1 mL bac water → 1,000 mcg/mL. A 40 mcg dose = 0.04 mL = 4 units.
Reconstitution: Reconstitute a 1 mg vial with 1 mL BAC water → 1 mg/mL (1000 mcg/mL). A 40 mcg dose = 0.04 mL = 4 units on a U-100 syringe.
Storage: Refrigerate after reconstitution (2–8 °C).

with Insulin
Avoid · severe
Both IGF-1 LR3 and insulin lower blood glucose through distinct pathways. Combined use carries serious risk of fatal hypoglycemia. This combination is used only in advanced clinical or elite bodybuilding contexts with full medical support.
Timing: Never combine without continuous glucose monitoring and medical supervision
with Growth Hormone
Caution · moderate
GH stimulates endogenous IGF-1 production; adding exogenous IGF-1 LR3 creates significant additive anabolic signaling. Hypoglycemia, acromegaly risk, and organ growth concerns at high doses.
Timing: Avoid concurrent use without medical supervision; use sequentially if at all
with HGH
Caution · moderate
HGH stimulates endogenous IGF-1 production; adding exogenous IGF-1 LR3 can cause insulin resistance, hypoglycemia, and acromegaly-like effects. Combined long-term use significantly increases cancer-growth risk.
Timing: Do not use simultaneously; run one at a time or use IGF-1 LR3 on off days from HGH

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