PeptideHormonal
Gonadorelin
Also known as Gonadorelin (GnRH), GnRH, gonadorelin gnrh
Typical dose
100–200 mcg
2–3×/week · SubQ · TRT adjunct
Half-life
~2-4 minutes
What is Gonadorelin?
Synthetic GnRH used to stimulate pituitary LH/FSH signaling.
How Gonadorelin works
Pulsatile GnRH receptor agonism increases gonadotropin release to support testicular steroidogenesis/spermatogenesis.
Gonadorelin dosage
- Typical dose
- Typical: 100–200 mcg SubQ, 2–3×/week (TRT adjunct). Clinical dosing varies.
Gonadorelin half-life
~2-4 minutes
Gonadorelin side effects
- Headache
- Flushing
- Desensitization with continuous exposure
Preparation & storage
- Preparation
- Mix a 2 mg vial with 2 mL bac water → 1,000 mcg/mL. A 100 mcg dose = 0.1 mL = 10 units.
- Reconstitution
- Reconstitute a 2 mg vial with 2 mL BAC water → 1 mg/mL. A 100 mcg dose = 0.1 mL = 10 units on a U-100 syringe.
Gonadorelin interactions
with HCG
Caution · mildGonadorelin pulses upstream (GnRH→LH/FSH); HCG mimics LH downstream. Stacking is mostly redundant; pick based on long-cycle vs short-cycle goals.
Timing: Choose one per protocol
Track Gonadorelin in Protokol.
Log doses, model half-lives, check interactions, and line it all up against your bloodwork. Free on iPhone and Android.
