Medication
Gabapentin
Half-life
~5-7 hours
What is Gabapentin?
Alpha2-delta ligand used for neuropathic pain, sleep support, and anxiety adjunct use.
How Gabapentin works
Reduces presynaptic calcium influx via alpha2-delta channel binding, lowering excitatory transmitter release.
Gabapentin half-life
~5-7 hours
Gabapentin side effects
- Sedation/dizziness
- Ataxia
- Withdrawal with abrupt discontinuation
