Supplement
Creatine Ethyl Ester
Half-life
~3–4 hours
What is Creatine Ethyl Ester?
Ethyl ester form of creatine claimed to improve absorption. Evidence not conclusively better than monohydrate.
How Creatine Ethyl Ester works
Ethyl ester modification was designed to improve lipid solubility and membrane permeability but research suggests it may hydrolyze to creatinine in the GI tract, potentially reducing bioavailability.
Benefits & uses
Common uses: Strength, power output, lean mass.
Creatine Ethyl Ester dosage
- Typical dose
- 2–3 g/day as alternative to monohydrate.
Creatine Ethyl Ester half-life
~3–4 hours (plasma)
Creatine Ethyl Ester side effects
May convert to creatinine (inactive metabolite) in the gut more than monohydrate. GI issues possible.
- May hydrolize to inactive creatinine faster than monohydrate
- Not clearly superior to monohydrate — monohydrate remains gold standard
Track Creatine Ethyl Ester in Protokol.
Log doses, model half-lives, check interactions, and line it all up against your bloodwork. Free on iPhone and Android.
