ProtokolPROTOKOL
Supplement

Citrus Bergamot

Half-life

~4–6 hours

What is Citrus Bergamot?

Extract from Calabrian bergamot fruit. Strong evidence for LDL reduction without statin side effects.

How Citrus Bergamot works

Bergamot polyphenols (neoeriocitrin, naringin, neohesperidin) inhibit HMG-CoA reductase (like statins) while also activating AMPK. Provides dual LDL-lowering and insulin-sensitizing effects.

Benefits & uses

Common uses: LDL reduction, HDL support, blood glucose, metabolic syndrome, triglycerides.

Citrus Bergamot dosage

Typical dose
500–1000 mg standardized Calabrian bergamot daily. Citrus Bergamot (NaturaGreen brand) most studied.

Citrus Bergamot half-life

~4–6 hours (polyphenols in plasma)

Citrus Bergamot side effects

Mild GI upset. Generally very well tolerated.

  • Mild GI discomfort in some individuals
  • May interact with CYP3A4 substrates (grapefruit family)

Track Citrus Bergamot in Protokol.

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For research and educational purposes only. This page is not medical advice and is not a recommendation to use any compound. Many compounds listed are not approved for human use, and some are prescription-only or controlled in your jurisdiction. Dosing figures are reference or observational reports. Talk to a qualified healthcare provider before starting, stopping, or changing anything. Protokol is for tracking purposes only.